Reza is a Consultant Cardiologist working at Westmead and St Leonards in Sydney, NSW. He has a special interest in cardiac imaging and preventive medicine.
Preventive Cardiology PCSK9 Inhibitors: Evolocumab and Inclisiran How PCSK9 inhibitors lower LDL cholesterol by about 50–60% — the mechanism, trial evidence, safety, and access in Australia. Dr Reza Moazzeni, MD FRACP·Consultant Cardiologist·Published 20 Aug 2023·Updated Jun 2026 PCSK9 (proprotein convertase… Read More »PCSK9 Inhibitors: The New Frontier in Cholesterol Management
https://youtu.be/Q70VY2m3bz8 Video: Bempedoic Acid mechanism of action Bempedoic acid is a novel treatment against hypercholesterolemia. It offers hope to patients struggling to control their cholesterol levels, mainly when traditional therapies fall short or cause undesirable side effects. High LDL cholesterol… Read More »Bempedoic Acid
Case Report · Clinical Amiodarone-Induced Leukocytoclastic Vasculitis: A Case Report A widely used antiarrhythmic, an unexpected purpuric rash, and the temporal clue that pointed to the diagnosis. Dr Reza Moazzeni, MD FRACP·Consultant Cardiologist·Published 21 June 2023·Updated 21 June 2026 Leukocytoclastic… Read More »Amiodarone-induced Leukocytoclastic Vasculitis (LCV)
Table of Contents What is Familial Hypercholesterolemia or FH? Familial hypercholesterolemia (FH) is a genetic disorder that causes high levels of low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. People with FH have a mutation in… Read More »Familial Hypercholesterolemia (FH): Diagnosis, Genetics
Unilateral leg swelling, where one leg increases in size relative to the other, often poses significant diagnostic challenges. It is less common and more difficult to diagnose than bilateral leg swelling, which is usually linked to heart failure and chronic… Read More »Unilateral Leg Swelling: Differential Diagnosis and Case Studies
Secondary mitral regurgitation is common in patients with heart failure and left ventricular systolic dysfunction. In many of these patients, the mitral valve itself is not the primary problem. The leak develops because the left ventricle enlarges, remodels, and distorts… Read More »Secondary Mitral Regurgitation in Heart Failure: Why GDMT and CRT Matter
What is cardiac asthma or cardiac cough? For centuries, we’ve understood that heart diseases can lead to symptoms like shortness of breath, cough, and even wheezing similar to what asthmatic patients experience. The term “Cardiac Asthma” has been casually used… Read More »Cardiac Asthma (Cardiac Cough): revisiting an old entity
Introduction The connection between weight loss and improved health is well-documented, with years of comprehensive research and numerous trials reinforcing this robust correlation. After recognising the transformative effects of shedding pounds, various diets, medical interventions, and surgical procedures have been… Read More »Sinus Bradycardia and Hypotension post Bariatric Surgery
Patient resource · Heartcare Sydney Swollen legs and ankles are usually venous, cardiac, drug-related or lymphatic. The first question to ask in leg swelling is whether one leg is swollen or both — that single observation narrows the causes of… Read More »Leg Swelling (Lower Limb Oedema): Causes, When to Worry, and What to Do
Most heart attacks are preventable. Roughly 80% of cardiovascular risk is shaped by what you eat, whether you smoke, how you move, your blood pressure, and how you handle stress and sleep. The five steps below are where the leverage… Read More »How to Prevent a Heart Attack: A 5-Step Plan
What is Nocebo and how it is different from Placebo? https://youtu.be/s6yVAOjFurE To better understand the difference between Placebo vs Nocebo, Let’s start with a familiar scenario. You visited your doctor, and she was concerned about your blood pressure. You knew… Read More »Statin Intolerance: Placebo vs Nocebo
Updated 2026 Coronary artery calcium, or CAC score, is one of the most useful tools for estimating the future risk of a heart attack in the right patient. In this comprehensive guide, I discuss when to consider a calcium score,… Read More »Coronary Calcium Score (Coronary Artery Calcification): Nuts and Bolts
CIED-related tricuspid regurgitation (TR) — particularly pacemaker-induced TR — is an under-recognised but clinically important cause of right heart failure (RHF). While heart failure is most commonly attributed to left ventricular dysfunction, a distinct group of patients presents with primary… Read More »Pacemaker-induced Tricuspid Regurgitation (CIED-related TR)
Can Amiodarone cause nephropathy (nephrotoxicity)? Amiodarone, a medication widely recognized for its numerous side effects, can lead to severe and even life-threatening conditions such as pulmonary toxicity, hepatotoxicity, and thyrotoxicity. This drug may also impact the kidneys, but Amiodarone-induced nephropathy… Read More »Amiodarone-induced nephropathy: A case study
Heart rhythm What is atrial fibrillation? Published 31 July 2018 · Reviewed 21 May 2026 · Dr Reza Moazzeni, Cardiologist The most common heart rhythm disorder — what it feels like, why it matters, and how it’s treated. A plain-language… Read More »Atrial Fibrillation (AF): Symptoms | Causes | Management | Video