Preventive Cardiology
Inclisiran (Leqvio): Twice-Yearly LDL Cholesterol Injection
How inclisiran silences PCSK9 production in the liver to lower LDL cholesterol by about 50% — the RNA-interference mechanism, the latest ORION and VictORION evidence, safety, and PBS access in Australia.
Dr Reza Moazzeni, MD FRACP·Consultant Cardiologist·Published 28 Aug 2023·Updated Jun 2026